Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

A research team has developed an innovative technique that enables precise modification of specific proteins within complex biological environments. The work was led by Professor Seung Soo Oh and Dr.

When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type 2 diabetes, neurodegenerative disorders, and cancers can develop. In a ...

"For histones, the time window for modifications is incredibly tight because their protein chains are very short," explains first author Denis Yudin, a doctoral student in Nenad Ban's lab. "NAC ...

Scientists at the Baylor College of Medicine say they have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called ...

An AI model that reveals how protein modifications link genetic mutations to disease has been developed. Researchers at Baylor College of Medicine (TX, USA) have developed an AI model that reveals how ...

Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including ...

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication. This ...

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan ...

Emulsions—mixtures of immiscible liquids such as oil and water—rely on surface‐active agents to stabilise dispersed droplets against coalescence and creaming. Proteins are among the most versatile ...