The ability to quantitatively probe diverse panels of proteins and their post-translational modifications (PTMs) across multiple samples would aid a broad spectrum of biological, biochemical, and ...

An increasing number of risk-stratifying genetic lesions in acute leukemia are being discovered and characterized. To translate this important and increasing volume of information from the research ...

In this interview, Ghaith Hamza from AstraZeneca talks to News-Medical Life Sciences about the basic principles of Affinity-Bead Assisted Mass Spectrometry (Affi-BAMS) and how Affi-BAMS can help ...

The field of proteomics has undergone rapid advancements over the last decade and protein microarrays have emerged as a promising technological platform for the challenging task of studying complex ...

The alternative text for this image may have been generated using AI. Reporting in Genome Research, Mark Chee and colleagues introduce an approach that looks set to realize the potential of randomly ...

Technique couples parallel bead-based screening with microarray-based comparisons of hits, as reported in Chemistry & Biology. A new method to screen libraries of 10 million or more compounds has been ...

JUPITER, FL, February 1, 2010 – The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage ...

For most researchers DNA microarrays are synonymous with high-throughput gene expression analysis. But they also are invaluable genotyping tools. Now that the International HapMap Project (see article ...

Microarrays have been critical components of biomedical and clinical research strategies since their first mention in a 1995 study. Initially designed to measure gene expression, or transcription, ...

Definition: A microarray is a small, flat substrate carrying an ordered grid of microscopic probe features, each containing a known biological molecule, that is used to measure many molecular targets ...

The search for new drug compounds is probably worse than looking for a needle in a haystack because scientists are limited in the size of the haystacks they can rummage through—time and money make it ...